DETAILED NOTES ON CONOLIDINE

These benefits, together with a earlier report showing that a little-molecule ACKR3 agonist CCX771 displays anxiolytic-like habits in mice,two aid the idea of focusing on ACKR3 as a singular strategy to modulate the opioid system, which could open up new therapeutic avenues for opioid-similar Problems.These results counsel that conolidine is in a p